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DLK1 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Clone Names | 100617300 |
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| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
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| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a transmembrane protein containing sixepidermal growth factor repeats. The protein is involved in thedifferentiation of several cell types, including adipocytes; it isalso thought to be a tumor suppressor. It is one of severalimprinted genes located in a region of on chr 14q32. Certainmutations in this imprinted region can cause phenotypes similar tomaternal and paternal uniparental disomy of chromosome 14 (UPD14).This gene is expressed from the paternal allele. A polymorphismwithin this gene has been associated with child and adolescentobesity. The mode of inheritance for this polymorphism is polaroverdominance; this non-Mendelian inheritance pattern was firstdescribed in sheep with the callipyge phenotype, which ischaracterized by muscle hypertrophy and decreased fat mass.
References
Yanai, H., et al. J. Biochem. 148(1):85-92(2010)Yu, F., et al. Liver Int. 30(5):703-714(2010)Akiyama, J., et al. Biochem. Biophys. Res. Commun. 393(4):662-667(2010)Wermter, A.K., et al. Eur. J. Hum. Genet. 16(9):1126-1134(2008)Charlier, C., et al. Genome Res. 11(5):850-862(2001)
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