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ING2 Antibody(Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9H160
Clone Names 100623195
Additional Information
Gene ID 3622
Other Names Inhibitor of growth protein 2, Inhibitor of growth 1-like protein, ING1Lp, p32, p33ING2, ING2, ING1L
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ING2
Synonyms ING1L
Function Seems to be involved in p53/TP53 activation and p53/TP53- dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs).
Cellular Location Nucleus. Note=Predominantly nuclear. Localized to chromatin and nuclear matrix Upon reduced PtdIns(5)P levels seems to be released from chromatin and, at least partially, translocated to the cytoplasm
Tissue Location Widely expressed. Higher expressed in colon-cancer tumor than in normal colon tissues.
Research Areas
Citations (0)

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This gene is a member of the inhibitor of growth (ING)family. Members of the ING family associate with and modulate theactivity of histone acetyltransferase (HAT) and histone deacetylase(HDAC) complexes and function in DNA repair and apoptosis.


Ythier, D., et al. Oncogene 29(44):5946-5956(2010)Larrieu, D., et al. EMBO Rep. 10(10):1168-1174(2009)Kumamoto, K., et al. Int. J. Cancer 125(6):1306-1315(2009)Borkosky, S.S., et al. J. Cancer Res. Clin. Oncol. 135(5):703-713(2009)Unoki, M., et al. FEBS Lett. 582(28):3868-3874(2008)

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$ 277.78
Cat# BP19411c
Availability: 2 weeks
Bulk Size

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