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PDCD2L Antibody(Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9BRP1 |
|---|---|
| Clone Names | 100603327 |
| Other Names | Programmed cell death protein 2-like, PDCD2L |
|---|---|
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PDCD2L |
|---|---|
| Function | Over-expression suppresses AP1, CREB, NFAT, and NF-kB transcriptional activation, and delays cell cycle progression at S phase. |
| Tissue Location | Higher expression in lung, colon, mammary gland, cervix, stomach and small intestine. EMBL; AC008747; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; AC092073; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; BC006146; AAH06146.1; -; mRNA CCDS; CCDS12438.1; - RefSeq; NP_115722.1; NM_032346.1 BioGRID; 124032; 33 IntAct; Q9BRP1; 25 STRING; 9606.ENSP00000246535; - iPTMnet; Q9BRP1; - PhosphoSitePlus; Q9BRP1; - BioMuta; PDCD2L; - DMDM; 74732907; - EPD; Q9BRP1; - jPOST; Q9BRP1; - MassIVE; Q9BRP1; - MaxQB; Q9BRP1; - PaxDb; Q9BRP1; - PeptideAtlas; Q9BRP1; - PRIDE; Q9BRP1; - ProteomicsDB; 78794; - Antibodypedia; 15737; 213 antibodies DNASU; 84306; - Ensembl; ENST00000246535; ENSP00000246535; ENSG00000126249 GeneID; 84306; - KEGG; hsa:84306; - UCSC; uc002nvj.4; human CTD; 84306; - EuPathDB; HostDB:ENSG00000126249.7; - GeneCards; PDCD2L; - HGNC; HGNC:28194; PDCD2L HPA; ENSG00000126249; Low tissue specificity MIM; 615661; gene neXtProt; NX_Q9BRP1; - OpenTargets; ENSG00000126249; - PharmGKB; PA144596395; - eggNOG; KOG2061; Eukaryota GeneTree; ENSGT00940000158339; - HOGENOM; CLU_034893_1_0_1; - InParanoid; Q9BRP1; - KO; K14801; - OMA; EEWVGVQ; - OrthoDB; 1181470at2759; - PhylomeDB; Q9BRP1; - TreeFam; TF354282; - PathwayCommons; Q9BRP1; - BioGRID-ORCS; 84306; 37 hits in 875 CRISPR screens ChiTaRS; PDCD2L; human GenomeRNAi; 84306; - Pharos; Q9BRP1; Tbio PRO; PR:Q9BRP1; - Proteomes; UP000005640; Chromosome 19 RNAct; Q9BRP1; protein Bgee; ENSG00000126249; Expressed in quadriceps femoris and 202 other tissues ExpressionAtlas; Q9BRP1; baseline and differential Genevisible; Q9BRP1; HS GO; GO:0005737; C:cytoplasm; IEA:InterPro GO; GO:0016020; C:membrane; HDA:UniProtKB GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW InterPro; IPR007320; PDCD2_C Pfam; PF04194; PDCD2_C; 1 1: Evidence at protein level; Acetylation; Cell cycle; Phosphoprotein; Reference proteome INIT_MET 1 /note="Removed" /evidence="ECO:0000244|PubMed:22814378" CHAIN 2..358 /note="Programmed cell death protein 2-like" /id="PRO_0000272645" MOD_RES 2 /note="N-acetylalanine" /evidence="ECO:0000244|PubMed:22814378" MOD_RES 20 /note="Phosphoserine" /evidence="ECO:0000244|PubMed:23186163" MOD_RES 22 /note="Phosphothreonine" /evidence="ECO:0000244|PubMed:23186163" SEQUENCE 358 AA; 39417 MW; 3946A6E4AD760155 CRC64; MAAVLKPVLL GLRDAPVHGS PTGPGAWTAS KLGGIPDALP TVAAPRPVCQ RCGQPLALVV QVYCPLEGSP FHRLLHVFAC ACPGCSTGGA RSWKVFRSQC LQVPEREAQD AQKQGNSLAA EDWCEGADDW GSDTEEGPSP QFTLDFGNDA SSAKDVDWTA RLQDLRLQDA VLGAAHPVPP GLPLFLPYYI CVADEDDYRD FVNLDHAHSL LRDYQQREGI AMDQLLSQSL PNDGDEKYEK TIIKSGDQTF YKFMKRIAAC QEQILRYSWS GEPLFLTCPT SEVTELPACS QCGGQRIFEF QLMPALVSML KSANLGLSVE FGTILVYTCE KSCWPPNHQT PMEEFCIIQE DPDELLFK |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
MGC13096, also known as PDCD2L, might play a role in apoptosis given evidence that over expression attenutates TNF alpha release in Daudi cells anad restrained proliferation of HEK293T cells.
References
Chen, Q., et al. Hum. Immunol. 69 (4-5), 259-265 (2008) :Chen, Q., et al. Cell Biochem. Funct. 26(2):141-145(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)Chen, Q., et al. Mol. Cell. Biochem. 280 (1-2), 185-191 (2005) :
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$ 277.78
Cat# BP19454c
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