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VAPA Antibody(C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9P0L0
Clone Names 100712119
Additional Information
Gene ID 9218
Other Names Vesicle-associated membrane protein-associated protein A, VAMP-A, VAMP-associated protein A, VAP-A, 33 kDa VAMP-associated protein, VAP-33, VAPA, VAP33
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms VAP33
Function Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites (PubMed:25447204). The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface (PubMed:25447204). With OSBPL3, may regulate ER morphology (PubMed:16143324). May play a role in vesicle trafficking (PubMed:11511104, PubMed:19289470).
Cellular Location Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Cell membrane; Single-pass type IV membrane protein. Cell junction, tight junction. Nucleus membrane {ECO:0000250|UniProtKB:Q9Z270}. Note=Present in the plasma membrane and in intracellular vesicles, together with SNARE proteins. May also associate with the cytoskeleton. Colocalizes with OCLN at the tight junction in polarized epithelial cells.
Tissue Location Ubiquitous.
Research Areas
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The protein encoded by this gene is a type IV membraneprotein. It is present in the plasma membrane and intracellularvesicles. It may also be associated with the cytoskeleton. Thisprotein may function in vesicle trafficking, membrane fusion,protein complex assembly and cell motility. Alternative splicingoccurs at this locus and two transcript variants encoding distinctisoforms have been identified.


Furuita, K., et al. J. Biol. Chem. 285(17):12961-12970(2010)Tuuf, J., et al. Biochem. Biophys. Res. Commun. 388(2):395-399(2009)Saita, S., et al. J. Biol. Chem. 284(20):13766-13777(2009)Prosser, D.C., et al. J. Cell. Sci. 121 (PT 18), 3052-3061 (2008) :Lohoff, F.W., et al. J Neural Transm 115(9):1339-1345(2008)

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$ 277.78
Cat# BP19461b
Availability: 2 weeks
Bulk Size

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