|Other Names||Beta-galactoside alpha-2, 6-sialyltransferase 2, Alpha 2, 6-ST 2, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2, 6-sialyltransferase 2, ST6Gal II, ST6GalII, hST6Gal II, Sialyltransferase 2, ST6GAL2, KIAA1877, SIAT2|
|Format||Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates. Has alpha-2,6- sialyltransferase activity toward oligosaccharides that have the Gal- beta-1,4-GlcNAc sequence at the non-reducing end of their carbohydrate groups, but it has weak or no activities toward glycoproteins and glycolipids.|
|Cellular Location||Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein|
|Tissue Location||Weakly expressed in some tissues, such as small intestine, colon and fetal brain.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Sialyltransferases, such as ST6GAL2 (EC 184.108.40.206), aretype II transmembrane proteins that catalyze the transfer of sialicacid from CMP-sialic acid to an acceptor carbohydrate, usually tothe terminal ends of carbohydrate chains.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Ikeda, M., et al. Biol. Psychiatry 67(3):263-269(2010)Lehoux, S., et al. Glycoconj. J. 27(1):99-114(2010)Trynka, G., et al. Gut 58(8):1078-1083(2009)Krzewinski-Recchi, M.A., et al. Eur. J. Biochem. 270(5):950-961(2003)
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