FCRL2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Clone Names | 110826131 |
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Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
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Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the immunoglobulin receptorsuperfamily and is one of several Fc receptor-like glycoproteinsclustered on the long arm of chromosome 1. The encoded protein hasfour extracellular C2-type immunoglobulin domains, a transmembranedomain and a cytoplasmic domain that contains oneimmunoreceptor-tyrosine activation motif and twoimmunoreceptor-tyrosine inhibitory motifs. This protein may be aprognostic marker for chronic lymphocytic leukemia. Alternativelyspliced transcript variants have been described, but theirbiological validity has not been determined.
References
Davila, S., et al. Genes Immun. 11(3):232-238(2010)Nuckel, H., et al. Eur. J. Haematol. 83(6):541-549(2009)Kazemi, T., et al. Cancer Immunol. Immunother. 58(6):989-996(2009)Kazemi, T., et al. Int. J. Cancer 123(9):2113-2119(2008)Li, F.J., et al. Blood 112(1):179-187(2008)
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