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CSF2RA Antibody(C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession P15509
Clone Names 90504057
Additional Information
Gene ID 1438
Other Names Granulocyte-macrophage colony-stimulating factor receptor subunit alpha, GM-CSF-R-alpha, GMCSFR-alpha, GMR-alpha, CDw116, CD116, CSF2RA, CSF2R, CSF2RY
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CSF2RA
Synonyms CSF2R, CSF2RY
Function Low affinity receptor for granulocyte-macrophage colony- stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.
Cellular Location Cell membrane; Single-pass type I membrane protein [Isoform 4]: Secreted.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is the alpha subunit ofthe heterodimeric receptor for colony stimulating factor 2, acytokine which controls the production, differentiation, andfunction of granulocytes and macrophages. The encoded protein is amember of the cytokine family of receptors. This gene is found inthe pseudoautosomal region (PAR) of the X and Y chromosomes.Multiple transcript variants encoding different isoforms have beenfound for this gene, with some of the isoforms being membrane-boundand others being soluble.

References

Mirza, S., et al. Biochem. J. 426(3):307-317(2010)Sun, S., et al. Brain Res. 1268, 13-16 (2009) :Suzuki, T., et al. J. Exp. Med. 205(12):2703-2710(2008)Martinez-Moczygemba, M., et al. J. Exp. Med. 205(12):2711-2716(2008)Hansen, G., et al. Cell 134(3):496-507(2008)

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$ 277.78
Cat# BP19497b
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