Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
ZBTB33 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Clone Names | 100525310 |
|---|
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
|---|---|
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a transcriptional regulator with bimodalDNA-binding specificity, which binds to methylated CGCG and also tothe non-methylated consensus KAISO-binding site TCCTGCNA. Theprotein contains an N-terminal POZ/BTB domain and 3 C-terminal zincfinger motifs. It recruits the N-CoR repressor complex to promotehistone deacetylation and the formation of repressive chromatinstructures in target gene promoters. It may contribute to therepression of target genes of the Wnt signaling pathway, and mayalso activate transcription of a subset of target genes by therecruitment of catenin delta-2 (CTNND2). Its interaction withcatenin delta-1 (CTNND1) inhibits binding to both methylated andnon-methylated DNA. It also interacts directly with the nuclearimport receptor Importin-α2 (also known as karyopherin alpha2or RAG cohort 1), which may mediate nuclear import of this protein.Alternatively spliced transcript variants encoding the same proteinhave been identified.
References
Zhang, J., et al. Microvasc. Res. 80(2):233-239(2010)Zhigalova, N.A., et al. Mol. Biol. (Mosk.) 44(2):263-274(2010)Dai, S.D., et al. Lung Cancer 67(2):205-215(2010)Soubry, A., et al. PLoS ONE 5 (2), E9203 (2010) :Dai, S.D., et al. BMC Cancer 9, 178 (2009) :
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Shipping Information
