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PIH1D1 Antibody(Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9NWS0
Clone Names 100617018
Additional Information
Gene ID 55011
Other Names PIH1 domain-containing protein 1, Nucleolar protein 17 homolog, PIH1D1, NOP17
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PIH1D1
Synonyms NOP17
Function Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles (PubMed:17636026). Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre- rRNA transcription (PubMed:22368283, PubMed:24036451). Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1 (PubMed:20864032). Positively regulates the assembly and activity of the mTORC1 complex (PubMed:24036451).
Cellular Location Nucleus {ECO:0000250|UniProtKB:Q9CQJ2}.
Tissue Location Expressed at low levels in normal mammary epithelial cells (at protein level) (PubMed:24036451). Highest expression in lung, leukocyte and placenta. Expressed at lower levels in brain, prostate, colon, heart, small intestine, liver, ovary, pancreas, skeletal muscle, spleen, testis and thymus (PubMed:21078300)
Research Areas
Citations (0)

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Background

PIH1D1 belongs to the PIH1 family.

References

Cloutier, P., et al. Methods 48(4):381-386(2009)McKeegan, K.S., et al. Mol. Cell. Biol. 27(19):6782-6793(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)Gonzales, F.A., et al. J. Mol. Biol. 346(2):437-455(2005)

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$ 277.78
Cat# BP19637c
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