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PIH1D1 Antibody(Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NWS0 |
|---|---|
| Clone Names | 100617018 |
| Gene ID | 55011 |
|---|---|
| Other Names | PIH1 domain-containing protein 1, Nucleolar protein 17 homolog, PIH1D1, NOP17 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PIH1D1 |
|---|---|
| Synonyms | NOP17 |
| Function | Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles (PubMed:17636026). Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre- rRNA transcription (PubMed:22368283, PubMed:24036451). Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1 (PubMed:20864032). Positively regulates the assembly and activity of the mTORC1 complex (PubMed:24036451). |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q9CQJ2}. |
| Tissue Location | Expressed at low levels in normal mammary epithelial cells (at protein level) (PubMed:24036451). Highest expression in lung, leukocyte and placenta. Expressed at lower levels in brain, prostate, colon, heart, small intestine, liver, ovary, pancreas, skeletal muscle, spleen, testis and thymus (PubMed:21078300) |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
PIH1D1 belongs to the PIH1 family.
References
Cloutier, P., et al. Methods 48(4):381-386(2009)McKeegan, K.S., et al. Mol. Cell. Biol. 27(19):6782-6793(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)Gonzales, F.A., et al. J. Mol. Biol. 346(2):437-455(2005)
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