MINOS1 Blocking Peptide (N-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q5TGZ0 |
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Other Accession | Q7TNS2 |
Gene ID | 440574 |
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Other Names | MICOS complex subunit MIC10, Mitochondrial inner membrane organizing system protein 1, MINOS1, C1orf151, MIC10 |
Target/Specificity | The synthetic peptide sequence is selected from aa 1-13 of HUMAN MINOS1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | MICOS10 (HGNC:32068) |
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Function | Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. |
Cellular Location | Mitochondrion inner membrane; Single-pass membrane protein. Note=The C-terminus is located in the intermembrane space (By similarity), while the location of the N- terminus has not been determined yet. As some programs predict the presence of 2 closely apposed membrane domains, it has been proposed that the protein may cross the membrane twice and that both termini may face the intermembrane space (PubMed:22114354). {ECO:0000250, ECO:0000269|PubMed:22114354} |
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Provided below are standard protocols that you may find useful for product applications.
Background
May play a role in mitochondrial architecture (By similarity).
References
Gregory S.G.,et al.Nature 441:315-321(2006).
Alkhaja A.K.,et al.Mol. Biol. Cell 23:247-257(2012).
Van Damme P.,et al.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
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