AACS Blocking Peptide (C-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q86V21 |
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Gene ID | 65985 |
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Other Names | Acetoacetyl-CoA synthetase, Acyl-CoA synthetase family member 1, Protein sur-5 homolog, AACS, ACSF1 |
Target/Specificity | The synthetic peptide sequence is selected from aa 539-553 of HUMAN AACS |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | AACS |
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Synonyms | ACSF1 |
Function | Converts acetoacetate to acetoacetyl-CoA in the cytosol (By similarity). Ketone body-utilizing enzyme, responsible for the synthesis of cholesterol and fatty acids (By similarity). |
Cellular Location | Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9JMI1} |
Tissue Location | Highly expressed in kidney, heart and brain, but low in liver. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Activates acetoacetate to acetoacetyl-CoA. May be involved in utilizing ketone body for the fatty acid-synthesis during adipose tissue development (By similarity).
References
Ohgami M.,et al.Biochem. Pharmacol. 65:989-994(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Gu T.,et al.Mol. Cell. Biol. 18:4556-4564(1998).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
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