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EXOC3 Blocking Peptide (C-term)

Synthetic peptide

     
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Product Information
Primary Accession O60645
Additional Information
Gene ID 11336
Other Names Exocyst complex component 3, Exocyst complex component Sec6, EXOC3, SEC6, SEC6L1
Target/Specificity The synthetic peptide sequence is selected from aa 524-537 of HUMAN EXOC3
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name EXOC3
Synonyms SEC6, SEC6L1
Function Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:O54921}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:O54921}. Cell projection, growth cone {ECO:0000250|UniProtKB:O54921}. Midbody. Golgi apparatus. Cell projection, neuron projection {ECO:0000250|UniProtKB:Q62825}. Note=Perinuclear in undifferentiated cells. Redistributes to growing neurites and growth cones during neuronal differentiation (By similarity). During mitosis, early recruitment to the midbody requires RALA, but not RALB, and EXOC2. In late stages of cytokinesis, localization to the midbody is RALB- dependent (PubMed:18756269). {ECO:0000250|UniProtKB:O54921, ECO:0000269|PubMed:18756269}
Tissue Location Expressed in epididymis (at protein level).
Research Areas
Citations (0)

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Background

Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

References

Li J.,et al.Mol. Cell. Proteomics 9:2517-2528(2010).
Jikuya H.,et al.DNA Res. 10:49-57(2003).
Schmutz J.,et al.Nature 431:268-274(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Yu W.,et al.Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.

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$ 277.78
Cat# BP21220b
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