CALY Blocking Peptide (N-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NYX4 |
|---|
| Gene ID | 50632 |
|---|---|
| Other Names | Neuron-specific vesicular protein calcyon, CALY, DRD1IP |
| Target/Specificity | The synthetic peptide sequence is selected from aa 60-74 of HUMAN CALY |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CALY |
|---|---|
| Synonyms | DRD1IP |
| Function | Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis. |
| Cellular Location | Cytoplasmic vesicle membrane; Single-pass membrane protein. Cell membrane; Single-pass membrane protein |
| Tissue Location | Expressed in the pyramidal cells of the prefrontal cortex, in hypothalamus and in caudate nucleus. No expression in spleen. Up-regulated in the prefrontal cortex of schizophrenic patients with nearly twice the levels of non-schizophrenics |

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Provided below are standard protocols that you may find useful for product applications.
Background
Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis.
References
Lezcano N.,et al.Science 287:1660-1664(2000).
Lezcano N.,et al.Science 314:1681-1681(2006).
Deloukas P.,et al.Nature 429:375-381(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Koh P.O.,et al.Arch. Gen. Psychiatry 60:311-319(2003).
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