RFX4 Blocking Peptide (C-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q33E94 |
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Gene ID | 5992 |
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Other Names | Transcription factor RFX4, Regulatory factor X 4, Testis development protein NYD-SP10, RFX4 |
Target/Specificity | The synthetic peptide sequence is selected from aa 684-700 of HUMAN RFX4 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | RFX4 |
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Function | Transcription factor that plays a role in early brain development. May activate transcription by interacting directly with the X-box. May activate transcription from CX3CL1 promoter through the X-box during brain development. May be required for neural tube ciliogenesis during embryogenesis (By similarity). |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00858}. |
Tissue Location | Isoform 1: Expressed in brain and gliomas (at protein level). Isoform 2: Testis-specific (at protein level). Isoform 3: Testis-specific (at protein level). Isoform 3: Expressed at a higher level in adult testes and ejaculated spermatozoa than in fetal testes Isoform 4: Testis-specific. |
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Provided below are standard protocols that you may find useful for product applications.
Background
May activate transcription by interacting directly with the X-box.
References
Blackshear P.J.,et al.Development 130:4539-4552(2003).
Matsushita H.,et al.Cancer Sci. 96:801-809(2005).
Huang X.,et al.J. Nanosci. Nanotechnol. 5:1236-1239(2005).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
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