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DAO Blocking Peptide (Center)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P14920 |
|---|
| Gene ID | 1610 |
|---|---|
| Other Names | D-amino-acid oxidase, DAAO, DAMOX, DAO, DAO, DAMOX |
| Target/Specificity | The synthetic peptide sequence is selected from aa 216-228 of HUMAN DAO |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | DAO |
|---|---|
| Synonyms | DAMOX |
| Function | Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. |
| Cellular Location | Peroxisome. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D- amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.
References
Momoi K.,et al.FEBS Lett. 238:180-184(1988).
Momoi K.,et al.Submitted (SEP-1990) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Fukui K.,et al.J. Biol. Chem. 267:18631-18638(1992).
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