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SPCS1 Blocking Peptide (Center)

Synthetic peptide

     
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Product Information
Primary Accession Q9Y6A9
Additional Information
Gene ID 28972
Other Names Signal peptidase complex subunit 1, 34--, Microsomal signal peptidase 12 kDa subunit, SPase 12 kDa subunit, SPCS1, SPC12
Target/Specificity The synthetic peptide sequence is selected from aa 86-100 of HUMAN SPCS1
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SPCS1
Synonyms SPC12
Function Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (PubMed:34388369). Dispensable for SPC enzymatic activity (By similarity).
Cellular Location Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P83362}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P83362}
Research Areas
Citations (0)
citation

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Background

Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.

References

Zhang Q.-H.,et al.Genome Res. 10:1546-1560(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Kalies K.-U.,et al.J. Biol. Chem. 271:3925-3929(1996).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).

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$ 277.78
Cat# BP21622c
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