|Other Names||Bile salt export pump, ATP-binding cassette sub-family B member 11, ABCB11, BSEP|
|Target/Specificity||The synthetic peptide sequence is selected from aa 1083-1097 of HUMAN ABCB11|
|Format||Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the secretion of conjugated bile salts across the canalicular membrane of hepatocytes in an ATP-dependent manner (PubMed:16332456). Transports taurine-conjugated bile salts more rapidly than glycine-conjugated bile salts (PubMed:16332456).|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed predominantly, if not exclusively in the liver, where it was further localized to the canalicular microvilli and to subcanalicular vesicles of the hepatocytes by in situ|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Involved in the ATP-dependent secretion of bile salts into the canaliculus of hepatocytes.
Strautnieks S.S.,et al.Nat. Genet. 20:233-238(1998).
Mol O.,et al.Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).
Mochizuki K.,et al.Am. J. Physiol. 292:G818-G828(2007).
Jansen P.L.M.,et al.Gastroenterology 117:1370-1379(1999).
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