PDE1A Blocking Peptide (N-Term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P54750 |
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Gene ID | 5136 |
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Other Names | Calcium/calmodulin-dependent 3', 5'-cyclic nucleotide phosphodiesterase 1A, Cam-PDE 1A, 61 kDa Cam-PDE, hCam-1, PDE1A |
Target/Specificity | The synthetic peptide sequence is selected from aa 43-57 of HUMAN PDE1A |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PDE1A (HGNC:8774) |
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Function | Calcium/calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cGMP and cAMP, which are key regulators of many important physiological processes. Has a higher efficiency with cGMP compared to cAMP. |
Tissue Location | Several tissues, including brain, kidney, testes and heart |
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Provided below are standard protocols that you may find useful for product applications.
Background
Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP.
References
Loughney K.,et al.J. Biol. Chem. 271:796-806(1996).
Michibata H.,et al.Biochim. Biophys. Acta 1517:278-287(2001).
Fidock M.D.,et al.Cell. Signal. 14:53-60(2002).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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