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PYGL Blocking Peptide (C-Term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P06737 |
|---|
| Gene ID | 5836 |
|---|---|
| Other Names | Glycogen phosphorylase, liver form, PYGL |
| Target/Specificity | The synthetic peptide sequence is selected from aa 829-843 of HUMAN PYGL |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PYGL (HGNC:9725) |
|---|---|
| Function | Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis. |
| Cellular Location | Cytoplasm, cytosol. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
References
Newgard C.B.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:8132-8136(1986).
Carty M.D.,et al.Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases.
Chang S.,et al.Hum. Mol. Genet. 7:865-870(1998).
Burwinkel B.,et al.Am. J. Hum. Genet. 62:785-791(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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