AKR7A3 Blocking Peptide (Center)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O95154 |
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Gene ID | 22977 |
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Other Names | Aflatoxin B1 aldehyde reductase member 3, 1.-.-.-, AFB1 aldehyde reductase 2, AFB1-AR 2, AKR7A3, AFAR2 |
Target/Specificity | The synthetic peptide sequence is selected from aa 207-217 of HUMAN AKR7A3 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | AKR7A3 |
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Synonyms | AFAR2 |
Function | Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. |
Cellular Location | Cytoplasm. |
Tissue Location | Expressed in colon, kidney, liver, pancreas, adenocarcinoma and endometrium. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
References
Knight L.P.,et al.Carcinogenesis 20:1215-1223(1999).
Praml C.,et al.Oncogene 22:4765-4773(2003).
Gregory S.G.,et al.Nature 441:315-321(2006).
Bodreddigari S.,et al.Chem. Res. Toxicol. 21:1134-1142(2008).
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