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RSL1D1 Blocking Peptide (C-Term)

Synthetic peptide

     
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Product Information
Primary Accession O76021
Other Accession Q5RCE6
Additional Information
Gene ID 26156
Other Names Ribosomal L1 domain-containing protein 1, CATX-11, Cellular senescence-inhibited gene protein, Protein PBK1, RSL1D1
Target/Specificity The synthetic peptide sequence is selected from aa 475-485 of HUMAN RSL1D1
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RSL1D1
Synonyms CATX11, CSIG {ECO:0000303|PubMed:1867864
Function Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage.
Cellular Location Nucleus, nucleolus. Note=Colocalizes with ING1 in the nucleolus after UV stress.
Tissue Location Expressed at high intensities in the heart, skeletal muscle, and placenta.
Research Areas
Citations (0)

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Background

Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage.

References

Huch G.,et al.Placenta 19:557-567(1998).
Petroziello J.,et al.Oncogene 23:7734-7745(2004).
Guo S.-Z.,et al.Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Martin J.,et al.Nature 432:988-994(2004).

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$ 277.78
Cat# BP22027b
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