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RSL1D1 Blocking Peptide (C-Term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O76021 |
|---|---|
| Other Accession | Q5RCE6 |
| Gene ID | 26156 |
|---|---|
| Other Names | Ribosomal L1 domain-containing protein 1, CATX-11, Cellular senescence-inhibited gene protein, Protein PBK1, RSL1D1 |
| Target/Specificity | The synthetic peptide sequence is selected from aa 475-485 of HUMAN RSL1D1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | RSL1D1 |
|---|---|
| Synonyms | CATX11, CSIG {ECO:0000303|PubMed:1867864 |
| Function | Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage. |
| Cellular Location | Nucleus, nucleolus. Note=Colocalizes with ING1 in the nucleolus after UV stress. |
| Tissue Location | Expressed at high intensities in the heart, skeletal muscle, and placenta. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage.
References
Huch G.,et al.Placenta 19:557-567(1998).
Petroziello J.,et al.Oncogene 23:7734-7745(2004).
Guo S.-Z.,et al.Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Martin J.,et al.Nature 432:988-994(2004).
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