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LSR Blocking Peptide (N-Term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q86X29 |
|---|
| Gene ID | 51599 |
|---|---|
| Other Names | Lipolysis-stimulated lipoprotein receptor, LSR, LISCH |
| Target/Specificity | The synthetic peptide sequence is selected from aa 30-43 of HUMAN LSR |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | LSR (HGNC:29572) |
|---|---|
| Synonyms | ILDR3, LISCH |
| Function | Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells (By similarity). Maintains epithelial barrier function by recruiting MARVELD2/tricellulin to tricellular tight junctions (By similarity). |
| Cellular Location | Cell membrane; Single-pass type I membrane protein. Cell junction, tight junction Note=Located at tricellular contacts. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells (By similarity).
References
Teramoto T.,et al.Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Otsuki T.,et al.DNA Res. 12:117-126(2005).
Grimwood J.,et al.Nature 428:529-535(2004).
Tang L.-Y.,et al.Mol. Cell. Proteomics 6:1952-1967(2007).
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