CHTF8 Blocking Peptide (C-Term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P0CG12 |
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Other Names | Chromosome transmission fidelity protein 8 homolog isoform 2, Decreased expression in renal and prostate cancer protein, CHTF8, DERPC |
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Target/Specificity | The synthetic peptide sequence is selected from aa 364-377 of HUMAN CHTF8 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | DERPC (HGNC:54084) |
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Function | Potential tumor suppressor. Inhibits prostate tumor cell growth, when overexpressed. |
Cellular Location | Nucleus. |
Tissue Location | Ubiquitously expressed, with abundant expression in kidney, skeletal muscle, testis, liver, ovary, and heart and moderate expression in prostate. Expression is significantly reduced in renal and prostate tumors. No differential expression in breast cancer cells, between lobular carcinoma and normal lobules |
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Provided below are standard protocols that you may find useful for product applications.
Background
Potential tumor suppressor. Inhibits prostate tumor cell growth, when overexpressed.
References
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Martin J.,et al.Nature 432:988-994(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Sun M.,et al.Mol. Med. 8:655-663(2002).
Green A.R.,et al.Breast Cancer Res. Treat. 113:59-66(2009).
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