Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
MD1 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O95711 |
|---|---|
| Clone Names | 2103126 |
| Gene ID | 9450 |
|---|---|
| Other Names | Lymphocyte antigen 86, Ly-86, Protein MD-1, LY86, MD1 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP2544a was selected from the N-term region of human MD1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | LY86 |
|---|---|
| Synonyms | MD1 |
| Function | May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression (By similarity). |
| Cellular Location | Secreted, extracellular space. Note=Associated with CD180 at the cell surface |
| Tissue Location | Highly expressed in B-cells, monocytes and tonsil. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
MD1 may cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. This protein is important for efficient CD180 cell surface expression. MD1 is highly expressed in B-cells, monocytes and tonsil. In monocytes, it is down-regulated by the cell-wall fraction of Mycobacterium bovis.
References
Begum, N.A., et al., Biochem. Biophys. Res. Commun. 256(2):325-329 (1999).Miura, Y., et al., Blood 92(8):2815-2822 (1998).Miyake, K., et al., J. Immunol. 161(3):1348-1353 (1998).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
