TAL1 Antibody (S122) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P17542 |
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Clone Names | 80125126 |
Gene ID | 6886 |
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Other Names | T-cell acute lymphocytic leukemia protein 1, TAL-1, Class A basic helix-loop-helix protein 17, bHLHa17, Stem cell protein, T-cell leukemia/lymphoma protein 5, TAL1, BHLHA17, SCL, TCL5 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP2754b was selected from the S122 region of human TAL1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | TAL1 |
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Synonyms | BHLHA17, SCL, TCL5 |
Function | Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation (By similarity). |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}. |
Tissue Location | Leukemic stem cell. |

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Provided below are standard protocols that you may find useful for product applications.
Background
TAL1 is implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. It serves as a positive regulator of erythroid differentiation.
References
Kassouf,M.T., Blood 112 (4), 1056-1067 (2008)Terme,J.M., J. Virol. 82 (16), 7913-7922 (2008)Brunet de la Grange,P., Stem Cells 26 (6), 1658-1662 (2008)

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