DLG7 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q15398 |
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Gene ID | 9787 |
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Other Names | Disks large-associated protein 5, DAP-5, Discs large homolog 7, Disks large-associated protein DLG7, Hepatoma up-regulated protein, HURP, DLGAP5, DLG7, KIAA0008 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | DLGAP5 |
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Synonyms | DLG7, KIAA0008 |
Function | Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells. |
Cellular Location | Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the spindle in mitotic cells. Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells |
Tissue Location | Abundantly expressed in fetal liver. Expressed at lower levels in bone marrow, testis, colon, and placenta |
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Provided below are standard protocols that you may find useful for product applications.
Background
DLG7 is potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. DLG7 is mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. DLG7 is key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells.
References
de Reynies, A., et al. J. Clin. Oncol. 27(7):1108-1115(2009)Wong, J., et al. Mol. Biol. Cell 19(5):2083-2091(2008)Gudmundsson, K.O., et al. Stem Cells 25(6):1498-1506(2007)
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