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Phospho-LHX2(Y213) Antibody Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P50458 |
|---|---|
| Clone Names | 80125119 |
| Gene ID | 9355 |
|---|---|
| Other Names | LIM/homeobox protein Lhx2, Homeobox protein LH-2, LIM homeobox protein 2, LHX2, LH2 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP3689a was selected from the region of human Phospho-LHX2-pY213. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | LHX2 |
|---|---|
| Synonyms | LH2 |
| Function | Acts as a transcriptional activator. Stimulates the promoter of the alpha-glycoprotein gene. Transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types (By similarity). |
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
LHX2 belongs to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. This protein may function as a transcriptional regulator. This protein can recapitulate or rescue phenotypes in Drosophila caused by a related protein, suggesting conservation of function during evolution.
References
Glenn,D.J., J. Biol. Chem. 274 (51), 36159-36167 (1999)Wu,H.K., Oncogene 12 (6), 1205-1212 (1996)
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