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GIMA1 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8WWP7 |
|---|
| Gene ID | 170575 |
|---|---|
| Other Names | GTPase IMAP family member 1, Immunity-associated protein 1, hIMAP1, GIMAP1, IMAP1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GIMAP1 |
|---|---|
| Synonyms | IMAP1 |
| Function | May regulate lymphocyte survival. Required for normal levels of mature T-lymphocytes and mature B-cells (By similarity). |
| Cellular Location | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P70224}; Single-pass type IV membrane protein. Golgi apparatus membrane {ECO:0000250|UniProtKB:P70224}; Single-pass type IV membrane protein |
| Tissue Location | Predominantly expressed in the spleen and to a lesser extent in the lymph nodes. Detected in T-cells |
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Provided below are standard protocols that you may find useful for product applications.
Background
GIMA1 belongs to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1.
References
Filen, J.J., et al. Mol. Cell Proteomics 8(1):32-44(2009)Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)Krucken, J., et al. Gene 341, 291-304 (2004)
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