TBC1D3C Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q6IPX1 |
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Other Accession | NP_001035372 |
Gene ID | 101060321;414060;729873 |
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Other Names | TBC1 domain family member 3C, TBC1D3C, TBC1D3D |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | TBC1D3C |
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Synonyms | TBC1D3D |
Function | Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity). |
Cellular Location | Cell membrane; Lipid-anchor. Note=Associated with lipid rafts. |
Tissue Location | Expressed in pancreas, thymus and testis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
TBC1D3C represents one of atleast 8 paralogs of TBC1D3 gene found on chromosome 17. These paralogs appear to be differentially expressed in human tissues. The proteins encoded by this gene family contain a TBC (Tre-2, Bub2p, and Cdc16p) domain, which is found in proteins involved in RAB GTPase signaling and vesicle trafficking.
References
Hodzic, D., et al. Genomics 88(6):731-736(2006)Paulding, C.A., et al. Proc. Natl. Acad. Sci. U.S.A. 100(5):2507-2511(2003)
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