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METL5 Blocking Peptide (Center)

Synthetic peptide

     
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Product Information
Primary Accession Q9NRN9
Other Accession NP_054887.2
Additional Information
Gene ID 29081
Other Names Methyltransferase-like protein 5, 211-, METTL5
Target/Specificity The synthetic peptide sequence is selected from aa 90-103 of HUMAN METTL5
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name METTL5 {ECO:0000303|PubMed:31328227, ECO:0000312|HGNC:HGNC:25006}
Function Catalytic subunit of a heterodimer with TRMT112, which specifically methylates the 6th position of adenine in position 1832 of 18S rRNA (PubMed:31328227, PubMed:32217665). N6-methylation of adenine(1832) in 18S rRNA is required for translation and embryonic stem cells (ESCs) pluripotency and differentiation (By similarity).
Cellular Location Nucleus. Cell junction, synapse, presynapse. Cell junction, synapse, postsynapse
Tissue Location Expressed from very early development (8 post- conceptual weeks) and expression persists through adulthood in multiple substructures of the brain, including the cerebellar cortex, hippocampus, and striatum.
Research Areas
Citations (0)

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References

Hillier, L.W., et al. Nature 434(7034):724-731(2005)

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$ 277.78
Cat# BP5382c
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