CEP78 Blocking Peptide (N-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q5JTW2 |
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Other Accession | NP_001092272.1, NP_115547.1 |
Gene ID | 84131 |
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Other Names | Centrosomal protein of 78 kDa, Cep78, CEP78, C9orf81 |
Target/Specificity | The synthetic peptide sequence is selected from aa 39-52 of HUMAN CEP78 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CEP78 |
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Synonyms | C9orf81 |
Function | May be required for efficient PLK4 centrosomal localization and PLK4-induced overduplication of centrioles (PubMed:27246242). May play a role in cilium biogenesis (PubMed:27588451). |
Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Note=Mainly localizes at the centriolar wall, but also found in the pericentriolar material (PubMed:27246242). Expressed in photoreceptor inner segment (PubMed:27588452). |
Tissue Location | Widely expressed (PubMed:27588451, PubMed:27588452). Expressed in different retinal cell types with higher expression in cone compared to rod cells (at protein level) (PubMed:27588452). |
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Provided below are standard protocols that you may find useful for product applications.
References
Petretti, C., et al. EMBO Rep. 7(4):418-424(2006)
Andersen, J.S., et al. Nature 426(6966):570-574(2003)
Casenghi, M., et al. Dev. Cell 5(1):113-125(2003)
Takahashi, M., et al. Mol. Biol. Cell 13(9):3235-3245(2002)
Mayor, T., et al. J. Cell Biol. 151(4):837-846(2000)
Golsteyn, R.M., et al. J. Cell Biol. 129(6):1617-1628(1995)
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