SHCBP1 Blocking Peptide (C-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8NEM2 |
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Other Accession | Q9Z179, NP_079021.3 |
Gene ID | 79801 |
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Other Names | SHC SH2 domain-binding protein 1, SHCBP1 |
Target/Specificity | The synthetic peptide sequence is selected from aa 515-528 of HUMAN SHCBP1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SHCBP1 |
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Function | May play a role in signaling pathways governing cellular proliferation, cell growth and differentiation. May be a component of a novel signaling pathway downstream of Shc. Acts as a positive regulator of FGF signaling in neural progenitor cells. |
Cellular Location | Midbody. Cytoplasm, cytoskeleton, spindle. Note=Displays weak localization to the spindle midzone in some early telophase cells and is concentrated at the midbody in late cytokinesis |

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Provided below are standard protocols that you may find useful for product applications.
References
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)
Obuse, C., et al. Genes Cells 9(2):105-120(2004)
Schmandt, R., et al. Oncogene 18(10):1867-1879(1999)
Robertson, N.G., et al. Genomics 23(1):42-50(1994)

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