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PLSCR2 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NRY7 |
|---|---|
| Other Accession | NP_065092.1 |
| Clone Names | 91230141 |
| Gene ID | 57047 |
|---|---|
| Other Names | Phospholipid scramblase 2, PL scramblase 2, Ca(2+)-dependent phospholipid scramblase 2, PLSCR2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PLSCR2 (HGNC:16494) |
|---|---|
| Function | May catalyze calcium-induced ATP-independent rapid bidirectional and non-specific movement of phospholipids (lipid scrambling or lipid flip-flop) between the inner and outer leaflet of the plasma membrane. |
| Cellular Location | Membrane {ECO:0000250|UniProtKB:O15162}; Single- pass type II membrane protein {ECO:0000250|UniProtKB:O15162} |
| Tissue Location | Expression of isoform 1 seems restricted to testis. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
PLSCR2 may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.
References
Sahu, S.K., et al. Biochim. Biophys. Acta 1790(10):1274-1281(2009)Yu, A., et al. J. Biol. Chem. 278(11):9706-9714(2003)Wiedmer, T., et al. Biochim. Biophys. Acta 1467(1):244-253(2000)
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