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Mouse GPR81-C7 Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8C131
Other Accession NP_780729
Additional Information
Gene ID 243270
Other Names Hydroxycarboxylic acid receptor 1, G-protein coupled receptor 81, Hcar1, Gpr81
Target/Specificity The synthetic peptide sequence is selected from aa 8-21 of MOUSE Hcar1
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Hcar1
Synonyms Gpr81
Function Acts as a receptor for L-lactate and mediates its anti- lipolytic effect through a G(i)-protein-mediated pathway.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Highly expressed in subcutaneous fat and omental fat and detectable in lower levels in brain and many other tissues High levels detected in epididymal and subcutaneous fat with slightly lower in omental fat, low levels are detected in the brain, skeletal muscle, kidney, liver and the pancreas (at protein level)
Research Areas
Citations (0)
citation

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Background

G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. Northern analyses revealed GPR81 expression in the pituitary.

References

Mao, M., et al., Genomics 83(6):989-999 (2004).
Lee, D.K., et al., Gene 275(1):83-91 (2001).

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$ 277.78
Cat# BP6362b
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