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CTSW Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P56202 |
|---|---|
| Clone Names | 80513090 |
| Gene ID | 1521 |
|---|---|
| Other Names | Cathepsin W, 3422-, Lymphopain, CTSW |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6570b was selected from the C-term region of human CTSW. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CTSW |
|---|---|
| Function | May have a specific function in the mechanism or regulation of T-cell cytolytic activity. |
| Cellular Location | Endoplasmic reticulum |
| Tissue Location | Expressed predominantly in natural killer cells, and in cytotoxic T cells. |
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Provided below are standard protocols that you may find useful for product applications.
Background
CTSW is a member of the peptidase C1 family, is a cysteine proteinase that may have a specific function in the mechanism or regulation of T-cell cytolytic activity. The protein is found associated with the membrane inside the endoplasmic reticulum of natural killer and cytotoxic T-cells.
References
Stoeckle,C., Exp. Hematol. 37 (2), 266-275 (2009)Wex,T., J. Immunol. 167 (4), 2172-2178 (2001)
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