SHC2 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P98077 |
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Clone Names | 80924202 |
Gene ID | 25759 |
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Other Names | SHC-transforming protein 2, Protein Sck, SHC-transforming protein B, Src homology 2 domain-containing-transforming protein C2, SH2 domain protein C2, SHC2, SCK, SHCB |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6621a was selected from the N-term region of human SHC2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SHC2 |
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Synonyms | SCK, SHCB |
Function | Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons (By similarity). |
Tissue Location | Expressed in brain. Expressed at high level in the hypothalamus and at low level in the caudate nucleus |
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Provided below are standard protocols that you may find useful for product applications.
Background
SHC2 is a signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. It is involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
References
Liu,H.Y., J. Biol. Chem. 277 (29), 26046-26056 (2002)
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