GBAS Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O75323 |
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Gene ID | 2631 |
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Other Names | Protein NipSnap homolog 2, NipSnap2, Glioblastoma-amplified sequence, GBAS, NIPSNAP2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | NIPSNAP2 (HGNC:4179) |
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Synonyms | GBAS |
Function | May act as a positive regulator of L-type calcium channels. |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:O55126}. Mitochondrion outer membrane |
Tissue Location | Widely expressed. Most abundant in heart and skeletal muscle |
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Provided below are standard protocols that you may find useful for product applications.
Background
Chromosomal region 7p12, which contains GBAS, is amplified in approximately 40% of glioblastomas, the most common and malignant form of central nervous system tumor.The predicted 286-amino acid protein contains a signal peptide, a transmembrane domain, and 2 tyrosine phosphorylation sites. The GBAS transcript is expressed most abundantly in heart and skeletal muscle. GBAS protein might be involved in vesicular transport.
References
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)Seroussi, E., et al. Gene 212(1):13-20(1998)Wang, X.Y., et al. Genomics 49(3):448-451(1998)
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