C9orf156 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9BU70 |
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Clone Names | 90625084 |
Gene ID | 51531 |
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Other Names | Nef-associated protein 1, 312-, Thioesterase NAP1, C9orf156, NAP1 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6938b was selected from the C-term region of human C9orf156. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | TRMO {ECO:0000303|PubMed:25063302, ECO:0000312|HGNC:HGNC:30967} |
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Function | S-adenosyl-L-methionine-dependent methyltransferase responsible for the addition of the methyl group in the formation of N6-methyl-N6-threonylcarbamoyladenosine at position 37 (m(6)t(6)A37) of the tRNA anticodon loop of tRNA(Ser)(GCU) (PubMed:25063302). The methyl group of m(6)t(6)A37 may improve the efficiency of the tRNA decoding ability (By similarity). |
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Provided below are standard protocols that you may find useful for product applications.
Background
C9orf156 hydrolyzes acyl-CoA thioesters (in vitro). It has a preference for substrates with medium chain length (C10-C14). Inactive towards substrates with C18 or C20 aliphatic chains. Its physiological function is not known.
References
Moreno,L.M., et.al., Hum. Mol. Genet. 18 (24), 4879-4896 (2009)
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