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SAST Blocking Peptide (N-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9R1L5 |
|---|---|
| Other Accession | Q811L6, O15021, Q60592, Q6P0Q8, Q810W7, Q9Y2H9 |
| Gene ID | 56527 |
|---|---|
| Other Names | Microtubule-associated serine/threonine-protein kinase 1, Syntrophin-associated serine/threonine-protein kinase, Mast1 {ECO:0000312|MGI:MGI:1861901} |
| Target/Specificity | The synthetic peptide sequence is selected from aa 25~39 of MOUSE Mast1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | Mast1 {ECO:0000312|MGI:MGI:1861901} |
|---|---|
| Function | Microtubule-associated protein essential for correct brain development (PubMed:30449657). Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. |
| Cellular Location | Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite. Note=Also localized in the soma of neurons (PubMed:30449657). Observed as punctate clusters in the processes of interneurons and along the cell body periphery Colocalizes with syntrophins at the cell membrane |
| Tissue Location | Expressed in the brain (PubMed:30449657). Expressed in the developing cortical plate, the intermediate zone and corpus callosal fibers that cross the midline (PubMed:30449657). Detected at low levels in the testis, liver and spleen (PubMed:30449657). Expressed in proximity to neuronal nuclei throughout the cortex and cerebellum, and in the vascular endothelium. Also detected in ependymal cells, the choroid plexus, and in developing spermatid acrosomes |
Research Areas
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Application Protocols
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$ 277.78
Cat# BP7247a
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