APOD Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P05090 |
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Clone Names | 80118133 |
Gene ID | 347 |
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Other Names | Apolipoprotein D, Apo-D, ApoD, APOD |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP7423a was selected from the N-term region of human APOD. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | APOD |
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Function | APOD occurs in the macromolecular complex with lecithin- cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts. |
Cellular Location | Secreted. |
Tissue Location | Expressed in liver, intestine, pancreas, kidney, placenta, adrenal, spleen, fetal brain tissue and tears |
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Provided below are standard protocols that you may find useful for product applications.
Background
APOD is a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2 microglobulin protein superfamily of carrier proteins, also known as lipocalins. This glycoprotein is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism.
References
Do Carmo,S., J. Neurosci. 28 (41), 10330-10338 (2008)Chen,Y., Brain Res. 1233, 196-202 (2008)Wei,Y.J., Biomarkers 13 (5), 535-548 (2008)
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