Fucokinase Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8N0W3 |
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Other Accession | NP_659496 |
Clone Names | 4011227 |
Gene ID | 197258 |
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Other Names | L-fucose kinase, Fucokinase, FUK |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8165a was selected from the N-term region of human Fucokinase. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | FCSK (HGNC:29500) |
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Function | Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides. |
Tissue Location | Expressed in fibroblasts. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Fucokinase belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis.
References
Clark, H.F., et al., Genome Res. 13(10):2265-2270 (2003).Hinderlich, S., et al., Biochem. Biophys. Res. Commun. 294(3):650-654 (2002).
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