GMPS Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P49915 |
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Clone Names | 81201117 |
Gene ID | 8833 |
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Other Names | GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase, GMPS |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8613c was selected from the Center region of human GMPS. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | GMPS |
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Function | Catalyzes the conversion of xanthine monophosphate (XMP) to GMP in the presence of glutamine and ATP through an adenyl-XMP intermediate. |
Cellular Location | Cytoplasm, cytosol. |
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Provided below are standard protocols that you may find useful for product applications.
Background
GMPS is involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division.
References
Nakamura,J., et.al., J. Biol. Chem. 270 (40), 23450-23455 (1995)Nakamura,J. et.al., J. Biol. Chem. 270 (13), 7347-7353 (1995)
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