CARD6 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9BX69 |
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Clone Names | 90904010 |
Gene ID | 84674 |
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Other Names | Caspase recruitment domain-containing protein 6, CARD6 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP9043c was selected from the Center region of human CARD6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CARD6 |
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Function | May be involved in apoptosis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
CARD6 is a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB.
References
Kim,S.S., et.al., Pathology 42 (1), 50-53 (2010)Olsen,J.V., et.al., Cell 127 (3), 635-648 (2006)
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