SERPINF2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P08697 |
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Gene ID | 5345 |
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Other Names | Alpha-2-antiplasmin, Alpha-2-AP, Alpha-2-plasmin inhibitor, Alpha-2-PI, Serpin F2, SERPINF2, AAP, PLI |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SERPINF2 |
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Synonyms | AAP, PLI |
Function | Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase- 3/TMPRSS7 and chymotrypsin. |
Cellular Location | Secreted. |
Tissue Location | Expressed by the liver and secreted in plasma. |
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Provided below are standard protocols that you may find useful for product applications.
Background
SERPINF2 encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway.
References
# Christensen, B., et al. J. Biol. Chem. 285(11):7929-7937(2010)# Cleary, D.B., et al. J. Thromb. Haemost. 7(11):1947-1949(2009)# Svenningsen, P., et al. J. Am. Soc. Nephrol. 20(2):299-310(2009)# Tseng, I.C., et al. Am. J. Physiol., Cell Physiol. 295 (2), C423-C431 (2008) # Lee, K.N., et al. Blood 103(10):3783-3788(2004)
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