|Other Names||DnaJ homolog subfamily C member 15, Cell growth-inhibiting gene 22 protein, Methylation-controlled J protein, MCJ, DNAJC15, DNAJD1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Negative regulator of the mitochondrial respiratory chain. Prevents mitochondrial hyperpolarization state and restricts mitochondrial generation of ATP (By similarity). Acts as an import component of the TIM23 translocase complex. Stimulates the ATPase activity of HSPA9.|
|Cellular Location||Mitochondrion inner membrane; Single-pass membrane protein|
|Tissue Location||Expressed at highest levels in heart, followed by liver and kidney.|
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Provided below are standard protocols that you may find useful for product applications.
Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)Witham, J., et al. Int. J. Cancer 122(11):2641-2645(2008)Hatle, K.M., et al. Mol. Cell. Biol. 27(8):2952-2966(2007)Lindsey, J.C., et al. Int. J. Cancer 118(2):346-352(2006)Strathdee, G., et al. Carcinogenesis 25(5):693-701(2004)
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