PDE6C Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P51160 |
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Gene ID | 5146 |
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Other Names | Cone cGMP-specific 3', 5'-cyclic phosphodiesterase subunit alpha', cGMP phosphodiesterase 6C, PDE6C, PDEA2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PDE6C |
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Synonyms | PDEA2 |
Function | As cone-specific cGMP phosphodiesterase, it plays an essential role in light detection and cone phototransduction by rapidly decreasing intracellular levels of cGMP. |
Cellular Location | Cell membrane; Lipid-anchor; Cytoplasmic side |
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Provided below are standard protocols that you may find useful for product applications.
Background
PDE6C is the alpha-prime subunit of cone phosphodiesterase, which is composed of a homodimer of two alpha-prime subunits and 3 smaller proteins of 11, 13, and 15 kDa.
References
Muradov, H., et al. J. Biol. Chem. 284(47):32662-32669(2009)Chang, B., et al. Proc. Natl. Acad. Sci. U.S.A. 106(46):19581-19586(2009)Thiadens, A.A., et al. Am. J. Hum. Genet. 85(2):240-247(2009)
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