RHG19 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q14CB8 |
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Gene ID | 84986 |
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Other Names | Rho GTPase-activating protein 19, Rho-type GTPase-activating protein 19, ARHGAP19 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ARHGAP19 |
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Function | GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. |
Cellular Location | Nucleus. |
Tissue Location | Strong expression in fetal heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Weak expression in adult pancreas, spleen, thymus, and ovary |
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Provided below are standard protocols that you may find useful for product applications.
Background
Members of the ARHGAP family, such as ARHGAP19, encode negative regulators of Rho GTPases (see RHOA; MIM 165390), which are involved in cell migration, proliferation, and differentiation, actin remodeling, and G1 cell cycle progression.
References
Lv, L., et al. DNA Seq. 18(3):184-189(2007)Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)Deloukas, P., et al. Nature 429(6990):375-381(2004)Jikuya, H., et al. DNA Res. 10(1):49-57(2003)
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