5NT1A Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9BXI3 |
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Gene ID | 84618 |
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Other Names | Cytosolic 5'-nucleotidase 1A, cN1A, Cytosolic 5'-nucleotidase IA, cN-I, cN-IA, NT5C1A |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | NT5C1A |
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Function | Catalyzes the hydrolysis of ribonucleotide and deoxyribonucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside (PubMed:11133996, PubMed:7599155, PubMed:8967393, PubMed:34814800). AMP is the major substrate but can also hydrolyze dCMP and IMP (PubMed:11133996, PubMed:7599155, PubMed:8967393, PubMed:34814800). |
Cellular Location | Cytoplasm. |
Tissue Location | Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas |
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Provided below are standard protocols that you may find useful for product applications.
Background
Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates.
References
Landers, J.E., et al. Proc. Natl. Acad. Sci. U.S.A. 106(22):9004-9009(2009)Lechward, K., et al. Acta Biochim. Biophys. Sin. (Shanghai) 41(4):280-284(2009)Fyrberg, A., et al. Nucleosides Nucleotides Nucleic Acids 25 (9-11), 1201-1204 (2006) :
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