Recombinant Murine IFN-λ2
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Description | IFN-λ-1,-2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and Interferons. All three IFN-λs uses a distinct receptor system composed of an IFN-λR1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14). Signaling through this receptor system induces antiviral defense similar but distinct than the type I Interferons. Recombinant murine IFN-λ2 is a 19.8 kDa protein containing 175 amino acid residues. |
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BiologicalActivity | Determined by its ability to activate STAT following receptor-ligand interaction. |
Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
Endotoxin | Endotoxin level is <0.1 ng/ µg of protein (<1EU/ µg). |
Protein Content | Verified by UV Spectroscopy and/or SDS-PAGE gel. |
Storage | -20°C |
Precautions | Recombinant Murine IFN-λ2 is for research use only and not for use in diagnostic or therapeutic procedures. |
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