TNF-beta, human recombinant protein
Tumor Necrosis Factor-β, TNFSF1, Lymphotoxin-α (LT-α)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P01374 |
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Calculated MW | 18.6 kDa |
Gene ID | 4049 |
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Gene Symbol | TNFB |
Other Names | Tumor Necrosis Factor-β, TNFSF1, Lymphotoxin-α (LT-α) |
Gene Source | Human |
Source | E. coli |
Assay&Purity | SDS-PAGE; ≥98% |
Assay2&Purity2 | HPLC; ≥98% |
Recombinant | Yes |
Results | <0.05 ng/ml |
Target/Specificity | TGF-beta |
Application Notes | Reconstitute in PBS to a concentration of 1 mg/ml. This solution can then be diluted into other aqueous buffers and store at 4°C for 1 week or –20°C for future use. For long term storage, it is recommended to add a carrier protein (0.1% HAS or BSA). |
Format | Lyophilized protein |
Storage | -20°C; Sterile filtered and lyophilized with no additives |
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Provided below are standard protocols that you may find useful for product applications.
Background
Tumor Necrosis Factor-β (TNF-β) is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells. Human TNF-β is a 18.6 kDa protein containing 171 amino acid residues.
References
Nedospasov S.A.,et al.Cold Spring Harb. Symp. Quant. Biol. 51:611-624(1986).
Nedwin G.E.,et al.J. Cell. Biochem. 29:171-181(1985).
Kobayashi Y.,et al.J. Biochem. 100:727-733(1986).
Gray P.W.,et al.Nature 312:721-724(1984).
Matsuyama N.,et al.FEBS Lett. 302:141-144(1992).
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